Antimicrobial de-escalation of treatment for healthcare-associated pneumonia within the Veterans Healthcare Administration
نویسندگان
چکیده
منابع مشابه
Outcomes Associated With Antimicrobial De-escalation of Treatment for Pneumonia Within the Veterans Healthcare Administration
De-escalation, an antimicrobial stewardship concept, involves narrowing broad-spectrum empiric antimicrobial therapy based on clinical data. Current health outcomes evidence is lacking to support de-escalation. Studying Veterans Healthcare Administration pneumonia patients, de-escalation was associated with improved length of stay without affecting 30-day readmission or 30-day Clostridium diffi...
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BACKGROUND Published guidelines for the treatment of healthcare-associated pneumonia (HCAP) recommend initial broad-spectrum antibiotics with appropriate de-escalation based on culture results. Guideline recommendations are based on data from intubated patients, in whom cultures are easily obtained. The approach to antibiotic de-escalation for culture-negative patients has not been addressed. C...
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TO THE EDITOR—We read with interest the meta-analysis by Chalmers et al [1], which demonstrates that the healthcareassociated pneumonia (HCAP) definition poorly predicts the presence of resistant pathogens. Based on these findings, the authors encourage treatment for HCAP to be guided by the local prevalence of multidrug-resistant pathogens. In hopes of constructing a local syndromic antibiogra...
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متن کاملHealthcare-associated pneumonia in the emergency department.
Emergency medicine clinicians frequently diagnose and treat patients with pneumonia. The recent recognition of healthcare-associated pneumonia (HCAP) mandates that emergency medicine clinicians remain current and able to distinguish this from community-acquired pneumonia. This article reviews the diagnosis and management of HCAP from the perspective of the emergency medicine clinician.
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ژورنال
عنوان ژورنال: Journal of Antimicrobial Chemotherapy
سال: 2015
ISSN: 0305-7453,1460-2091
DOI: 10.1093/jac/dkv338